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A previous study showed that sulforaphane treatment could increase SOD to decrease mitochondrial damage and preserve mitochondrial microstructure after kidney transplantation ( via inhibiting Keap1 and upregulating Nrf2 (Mohammad et al., 2022)

Retrieved from Singh, G., Krauthamer, M., & Bjalme-Evans, M

Blood 112(7):2886-2895, 2008

Notable concerns with metformin use include lactic acidosis and intolerable gastrointestinal upset

it does not cause elevations in prolactin, FSH (follicle-stimulating hormone), LH (luteinizing hormone), or TSH (thyroid-stimulating hormone) levels, nor does it stimulate the secretion of ACTH (adrenocorticotropic hormone) or cortisol

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